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A2 If we substitute η∗ and η∗ within the methods (6), we've the following optimality system: 1 2 dX∗ ∗ ∗ ∗ ∗ = s − µX (t) − okay(1 − η1(t))V (t)X (t), dt dY∗ −λτ ∗ ∗ ∗ ∗ ∗ ∗ = e ok(1 − η1(t))V (t − τ)X (t − τ) − δY (t) − pY (t)Z (t), dt dD∗ ∗ ∗ ∗ ∗ = (1 − η2(t))aY (t) − δD (t) − βD (t) dt dV∗ ∗ ∗ ∗ ∗ = βD (t) − uV (t) − qV (t)W (t), dt dW∗ ∗ ∗ ∗ = gV (t)W (t) − hW (t), dt dZ∗ ∗ ∗ ∗ = cY (t)Z (t) − bZ (t), dt then,  λ0 (t) = 1 + λ (t) µ + okay 1 − η∗(t) V∗(t)  1 1 1  ∗ −λτ ∗  +χ<>,t −τ](t)λ2 t + τ η1 t + τ − 1 ke V (t),  f  zero ∗ ∗ ∗  λ2(t) = λ2(t)δ − λ3(t)a 1 − η2(t) − cZ (t)λ6(t) + pZ (t)λ2(t),  λ0 (t) = λ (t) δ + β − βλ (t) 3 three 4 zero ∗ ∗ ∗ (20)  λ4(t) = λ1(t) okay(1 − η1(t))X (t) + λ4(t)(u + qW (t))   +χ (t)λ (t + τ) ke−λτ(η∗(t + τ) − 1)X∗(t) ,  tf −τ] 2 1   λzero (t) = 1 + λ (t)qV∗(t) + λ (t) h − cV∗(t)  5 4 5  λzero (t) = 1 + λ (t)pY∗(t) + λ (t) b − cY∗(t) 6 2 6 λi(tf ) = 0, i = 1,.. 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